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Best aspirins - September 2025

Last Updated - September 18, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

GenCare

GenCare - Low Dose Aspirin 81mg for Adults Coated (NSAID) 500 Tablets | Adult Low Dose | Enteric Coated Aspirin Pills | Muscle Pain & Menstrual Pain Relief | Fever Reducer | Generic Bayer

GenCare

$8.99

More Details
Main highlights
- PAIN RELIEF - Each coated tablet can be used for the temporary relief of muscle pain, menstrual pain and minor pain of arthritis. Talk to your doctor or healthcare provider before use as a temporary pain reliever or for life saving benefits. Do not take if allergic to aspirin
- LOW DOSE - Each enteric coated tablet contains 81mg of active ingredient aspirin (NSAID - nonsteroidal anti-inflammatory drug). These coated tablets are gluten free, caffeine free for use as an adult low dose aspirin pain reliever tablet.
- CAFFEINE FREE - These low dose adult aspirin coated tablets are caffeine free and gluten free. Each coated tablet is small and easy to swallow. Drink a full glass of water with each dose. Adults and children 12 years and over, do not exceed 12 tablets in 24 hours.
- BEST VALUE SAVINGS – Always enjoy Low Dose Adult Aspirin (81mg) on hand for you and your family. Our value savings bottles contain 500 individual tablets so you can stock up and enjoy bulk savings. For children under 12 consult a doctor before use.
$8.99
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer

Bayer Extra Strength 500mg Aspirin Plus Caffeine for Powerful Pain Relief, 200 Coated Caplets

Bayer

$17.17

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Main highlights
- Targeted Back and Body Relief: Bayer Back and Body Extra Strength Aspirin provides fast, proven relief of backache and muscle aches and pains
- Powerful Pain Reliever: Dual action formula containing aspirin and caffeine for a pain relief booster provides fast relief at the site of pain, when taken as directed
- Free From: Each coated pain medicine tablet is free of sodium and is coated to make it easier for swallowing
- Aspirin Plus Caffeine: This pain medicine for adults and children over 12 contains 500mg aspirin, as well as 32.5mg caffeine to help boost the pain-relieving effects of aspirin
- 125 Years of Relief: Bayer Aspirin has been a leading aspirin brand in pain relief
$17.17
3

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

St. Joseph

St. Joseph Aspirin Pain Reliever (NSAID) 81mg, Enteric Safety Coated, Adult Low Dose Regimen, 365 ct (1 Year Supply)

St. Joseph

$16.79

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Main highlights
- Put a Little Love in Your Heart: You put your heart into everything you love. For generations, St. Joseph Low Dose Aspirin has been a staple of households as America’s first and most trusted low dose aspirin for families.
- Pain Relief: For the temporary relief of minor aches and pains.
- Low Dose Aspirin Regimen: Recommended by doctors and leading health organizations to help some individuals prevent a recurring heart attack or ischemic stroke.
- Easy-to-Swallow Enteric Coated Low Dose Aspirin: Safety coated micro tablets delay aspirin release so that the tablet can pass through the stomach before dissolving to help reduce the potentially irritating effects of aspirin on the stomach lining.
- Consult Your Doctor: Aspirin therapy is not right for everyone, so always talk to your doctor before starting or changing any aspirin regimen.
$16.79
4

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer

Bayer Aspirin Low Dose 81 mg, Enteric Coated Tablets, Doctor Recommended, Secondary Prevention of Cardiovascular Disease, 300 Safety Coated Tablets

Bayer

$14.97

More Details
Main highlights
- Relieves Minor Aches and Pains: 81mg aspirin can also be taken for temporary relief of minor body aches and pains
- Protect Your Heart: Bayer Aspirin Low Dose can be used by adults whose doctors recommend a low dose aspirin regimen
- Leading Aspirin Brand: Bayer Aspirin has been a leading brand for second cardiovascular prevention
- Easy to Swallow: Each safety coated 81mg aspirin tablet is coated for easier swallowing and stomach protection, and is also caffeine and sodium-free
- Aspirin is not appropriate for everyone, so be sure to talk to your doctor before you begin an aspirin regimen
- #1 Doctor Recommended: Bayer Aspirin is the #1 doctor recommended aspirin brand
$14.97
5
Best Value
10% Off

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Bayer
10% Off

Bayer Genuine Aspirin 325 mg, Pain Reliever and Fever Reducer, Head, Muscle, Minor Arthritis, Back, Tooth, and Menstrual Pain, 300 Coated Tablets

Bayer

$14.81

$16.46
(10% Off)

More Details
Main highlights
- Multi-Symptom Pain Reliever and Fever Reducer: Genuine Bayer Aspirin provides proven relief of headache, backache, muscle pain, toothache, menstrual pain, as well as minor arthritis pain relief, and reduces fever
- Helps Prevent Another Heart Attack or Ischemic Stroke: Genuine Bayer Aspirin can help prevent another heart attack or clot-related (ischemic) stroke
- Free From: Each pain medicine tablet is free of caffeine and sodium and is coated to make it easier for swallowing
- Aspirin is not appropriate for everyone, so be sure to talk to your doctor before you begin an aspirin regimen
- 325 Mg Per Tablet: Each coated tablet of Genuine Bayer Aspirin contains 325 mg of the active ingredient aspirin (NSAID)*
- 125 Years of Relief: Bayer Aspirin has been a leading aspirin brand in pain relief
$14.81
$16.46 (10% Off)

Best aspirins - September 2025

GenCare - Low Dose Aspirin 81mg for Adults Coated (NSAID) 500 Tablets | Adult Low Dose | Enteric Coated Aspirin Pills | Muscle Pain & Menstrual Pain Relief | Fever Reducer | Generic Bayer

Bayer Extra Strength 500mg Aspirin Plus Caffeine for Powerful Pain Relief, 200 Coated Caplets

St. Joseph Aspirin Pain Reliever (NSAID) 81mg, Enteric Safety Coated, Adult Low Dose Regimen, 365 ct (1 Year Supply)

Bayer Aspirin Low Dose 81 mg, Enteric Coated Tablets, Doctor Recommended, Secondary Prevention of Cardiovascular Disease, 300 Safety Coated Tablets

Bayer Genuine Aspirin 325 mg, Pain Reliever and Fever Reducer, Head, Muscle, Minor Arthritis, Back, Tooth, and Menstrual Pain, 300 Coated Tablets

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